Welcome to Conformetrix
Conformetrix Ltd is a pre-clinical drug discovery company. Our ligand-based approach to discovery provides unique insight into hit identification and lead optimisation. It also rapidly identifies novel chemical scaffolds for drugging any therapeutic target.
How? By using the templates provided by Mother Nature herself: the natural ligands for important receptor proteins such as GPCRs and ion-channels.

The dynamic '4D-structure' of the natural polysaccharide ligand hyaluronan
Our platform technology is a set of proprietary analytical tools
that accurately determines the preferred 3D-shapes of these natural
ligands and the drugs that mimic them. It also quantifies the dynamic
range of movement around these preferred 3D-shapes (what we call a
molecules' 4D-structure). This information is key not only to
understanding how drugs work but also how to quickly & efficiently
improve new compounds in development.
Conformetrix is the only company in the world with this capability. The insight it provides gives Conformetrix its competitive edge: allowing us to finally realise true ligand-based drug discovery.
For more detail on how we are using these 4D-structures to realise a new paradigm in ligand-based discovery please click here.
To learn more about Conformetrix's core platform technology please follow this link.
CRO services
Conformetrix also offers access to its platform technology on a straight fee-for-service basis to key clients in the drug discovery industry.
Meet Conformetrix
Conformetrix will next attend the BIO 2009 International Convention in Atlanta (18th - 20th May).